Clive et Elsa sont des superstars de la science : ils ont réussi à combiner l'ADN de différentes espèces animales pour obtenir de fantastiques hybrides. Ils sont amoureux l'un de l'autre autant que de leur travail et veulent à présent passer à l'étape suivante : fusionner de l'ADN animal et de l'ADN humain.Lorsque le laboratoire pharmaceutique qui les finance refuse de les soutenir, Clive et Elsa décident de poursuivre leurs expériences en secret. Ils créent Dren, une créature étonnante dont la croissance rapide la fait devenir adulte en quelques mois. Alors qu'ils redoublent d'efforts pour préserver leur secret, leur intérêt scientifique pour Dren se mue peu à peu en attachement. Dren finira par dépasser les rêves les plus fous du couple... et leurs pires cauchemars.

Où le regarder au Canada

En location

CosmoGo

À l’achat

Distribution

Adrien Brody

Clive Nicoli

Sarah Polley

Elsa Kast

Delphine Chanéac

Dren

Brandon McGibbon

Gavin Nicoli

Simona Măicănescu

Joan Chorot

David Hewlett

William Barlow

Abigail Chu

Child Dren

🎭

Doug Hicton

Lab tech (uncredited)

Adrien Brody — Clive Nicoli

Adrien Nicholas Brody (born April 14, 1973) is an American actor and visual artist. Prolific in both independent films and blockbusters, he has received various accolades, including two Academy Awards, a BAFTA Award, and a Golden Globe Award, with nominations for three Emmy Awards and a Laurence Olivier Award. In 2025, Time magazine listed him as one of the world's 100 most influential people.

Sarah Polley — Elsa Kast

Sarah Ellen Polley OC (born January 8, 1979) is a Canadian filmmaker, political activist and retired actress. She first garnered attention as a child actress for her role as Ramona Quimby in the television series Ramona, based on Beverly Cleary's books. This subsequently led to her role as Sara Stanley in the Canadian television series Road to Avonlea (1990–1996). She has starred in many feature f

Delphine Chanéac — Dren

Delphine Chanéac is a French model, actress and disc jockey. Chanéac worked in the French cinema, appearing in European films and television in the late 1990s and 2000s. She is best known for her role as Pauline in the French sitcom La Vie Devant Nous and for portraying the genetic hybrid Dren in the Canadian science fiction/horror movie Splice, shaving her head for the role. She also starred in t