Enola takes on her first official case as a detective, but to solve the mystery of a missing girl, she'll need help from friends — and brother Sherlock.

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Cast

Millie Bobby Brown

Enola Holmes

Henry Cavill

Sherlock Holmes

David Thewlis

Grail

Louis Partridge

Tewkesbury

Susan Wokoma

Edith

Adeel Akhtar

Lestrade

Sharon Duncan-Brewster

Mira Troy

Helena Bonham Carter

Eudoria Holmes

Sofia Stavrinou

Young Enola

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John Parshall

Young Sherlock

Millie Bobby Brown — Enola Holmes

Millie Bonnie Bongiovi (born 19 February 2004), a British actress, is professionally known as Millie Bobby Brown. She gained recognition for playing Eleven in the Netflix science fiction series Stranger Things (2016–2025), for which she received nominations for two Primetime Emmy Awards. Brown has starred in the monster film Godzilla: King of the Monsters (2019) and its sequel Godzilla vs. Kong (2

Henry Cavill — Sherlock Holmes

Henry William Dalgliesh Cavill (born May 5, 1983) is a British actor. He is known for his portrayal of Charles Brandon in Showtime's The Tudors (2007–2010), DC Comics character Superman in the DC Extended Universe, Geralt of Rivia in the Netflix fantasy series The Witcher (2019–present), as well as Sherlock Holmes in the Netflix film Enola Holmes (2020).

David Thewlis — Grail

David Wheeler (born March 20, 1963), better known as David Thewlis, is an English actor and filmmaker. He is known as a character actor and has appeared in a wide variety of genres in both film and television. He has received the Cannes Film Festival Award for Best Actor and nominations for two BAFTA Awards, Golden Globe Award, Primetime Emmy Award and a Screen Actors Guild Award.